Man lying in bed, struggling to sleep
Jun 22 2025

Don't Snooze on Sleep in Your 30s and 40s

Written By Tracy Hamilton, CCSH, RRT-SDS, RPSGT, RST
Man lying in bed, struggling to sleep
Summary

Sleep should be a priority for good health now and in the future. After age 30, you may need to take extra steps to consistently get 7-9 hours of sleep.

Getting good sleep isn’t just about feeling rested — it is essential for keeping your brain sharp, focused and healthy. 

In your 30s and 40s, you often experience a decline in both the quality and quantity of sleep due to changes in your body, lifestyle and stress levels. If not addressed, these changes can increase the risk of memory problems, dementia and Alzheimer's disease later in life.

What Happens to Sleep in Your 30s?

In your 30s, stress and natural hormonal changes can make getting the recommended 7 to 9 hours of sleep each night difficult. Having a demanding lifestyle — a busy career, young children, unpredictable schedules, etc. — frequently leads to stress and late nights. 

That can cause cortisol, the stress hormone, to remain elevated. At the same time, the body’s production of melatonin, the hormone that helps you fall asleep, naturally begins to decline. This increase in cortisol and decrease in melatonin makes it harder to unwind, fall asleep and stay asleep throughout the night. 

What Changes in Your 40s?

By your 40s, sleep problems often become more noticeable. Many people experience “sleep fragmentation,” meaning they wake up more often during the night and get less deep, restful sleep. People in their 40s are also more prone to developing chronic sleep disorders such as insomnia or sleep apnea — both of which severely impact the brain’s ability to recover during sleep – making it harder to feel refreshed in the morning.

Why This Matters: The Link to Dementia and Alzheimer’s

While you’re sleeping, your brain does its most important cleanup work. During deep sleep, your brain clears out harmful waste, including proteins like beta-amyloid and tau. These proteins — known to build up in the brains of people with Alzheimer’s — can begin accumulating in the brain decades before symptoms appear, so often starting in midlife.

Because of this, sleep quality in your 30s and 40s isn’t just about feeling rested — it’s a crucial part of brain maintenance that may determine your cognitive health in older age. If you don’t get enough deep sleep, your brain doesn’t have time to remove these toxins. Over the years, this can increase your risk of memory loss and diseases like dementia and Alzheimer’s. In fact, research shows that people with poor sleep in their 30s and 40s are more than twice as likely to develop cognitive problems later in life.

What You Can Do

  • Stick to a regular sleep schedule. Try to go to bed and wake up at the same time each day.
  • Limit Screen time and caffeine before bed.
  • Create a relaxing bedtime routine.
  • Get checked for sleep disorders if you have trouble falling asleep or staying asleep.
  • Make sleep a priority, not a luxury.

Final Thought

Sleep isn’t just about rest — it’s a powerful tool for protecting your brain. What you do in your 30s and 40s can shape your mental health for decades to come. Protect your sleep now, and you’ll be protecting your memory and thinking skills well into the future. 

Tracy Hamilton
Tracy Hamilton
Meet the author

Tracy Hamilton, CCSH, RRT-SDS, RPSGT, RST

Tracy Hamilton, CCSH, RRT-SDS, RPSGT, RST, is a sleep navigator with North Mississippi Medical Center’s Sleep Disorders Center. Tracy is certified in Clinical Sleep Health and is a Registered Respiratory Therapist with additional sleep disorders specialties. After five years of prior respiratory and sleep experience, Tracy joined NMMC in 2001.

Well Rested

NMMC's Sleep Disorders Centers help people overcome sleep apnea, narcolepsy, chronic insomnia and other sleep disorders.

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